Hideki Ueno, MD, PhD


Professor
Department of Microbiology
Global Health and Emerging Pathogens Institute
Icahn School of Medicine at Mount Sinai

Professor
Department of Immunology
Graduate School of Medicine, Kyoto University

Primary Investigator
Institute for the Advanced Study of Human Biology, Kyoto University

http://labs.icahn.mssm.edu/uenolab/dr-ueno/


Hideki Ueno, M.D, Ph.D. is a Professor at the Global Health and Emerging Pathogens Institute in the Department of Microbiology. With more than 15 years experience in human immunology, Dr. Ueno’s research focuses on the human adaptive immune system –  the major immunological protection mechanism in charge of generation and maintenance of antigen-specific immune responses. The major research topic in the past decade in the Dr. Ueno Laboratory has been the biology of human T follicular helper (Tfh) cells, a CD4+ T cell subset fundamental for the generation of antibody responses. His laboratory has identified functionally distinct subsets within blood circulating Tfh cells in humans. This seminal work has been cited more than 600 times. This work has led to their identification of cTfh1 cells in charge of antibody responses following seasonal influenza vaccination. The Dr. Ueno laboratory also identified multiple key factors and pathways promoting the differentiation of human Tfh cells, including the IL-12-STAT4 axis.

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Latest IDIGH Publications

  1. Luz, P. M., Torres, T. S., Almeida-Brasil, C. C., Marins, L. M. S., Veloso, V. G., Grinsztejn, B., Cox, J. & Moodie, E. E. M.
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    High-Risk Sexual Behavior, Binge Drinking and Use of Stimulants are Key Experiences on the Pathway to High Perceived HIV Risk Among Men Who Have Sex with Men in Brazil
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    AIDS and behavior
  2. Sulis, G., Daniels, B., Kwan, A., Gandra, S., Daftary, A., Das, J. & Pai, M.
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    Antibiotic overuse in the primary health care setting: a secondary data analysis of standardised patient studies from India, China and Kenya
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    BMJ global health
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    5
  3. Rebeiro, P. F., Jenkins, C. A., Bian, A., Lake, J. E., Bourgi, K., Moore, R. D., Horberg, M. A., Matthews, W. C., Silverberg, M. J., Thorne, J., Mayor, A. M., Lima, V. D., Palella, F. J., Saag, M. S., Althoff, K. N., Gill, M. J., Wong, C., Klein, M. B., Crane, H. M., Marconi, V. C., Shepherd, B. E., Sterling, T. R. & Koethe, J. R.
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    Risk of Incident Diabetes Mellitus, Weight Gain, and their Relationships with Integrase Inhibitor-based Initial Antiretroviral Therapy Among Persons with HIV in the US and Canada
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    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  4. Mendel, A., Ennis, D., Go, E., Bakowsky, V., Baldwin, C., Benseler, S. M., Cabral, D. A., Carette, S., Clements-Baker, M., Clifford, A., Cohen Tervaert, J. W., Cox, G., Dehghan, N., Dipchand, C., Dhindsa, N., Famorca, L., Fifi-Mah, A., Garner, S., Girard, L.-P., Lessard, C., Liang, P., Noone, D., Makhzoum, J.-P., Milman, N., Pineau, C. A., Reich, H. N., Rhéaume, M., Robinson, D. B., Rumsey, D. G., Towheed, T. E., Trudeau, J., Twilt, M., Yacyshyn, E., Yeung, R., Barra, L., Khalidi, N. & Pagnoux, C.
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    CanVasc consensus recommendations for the management of antineutrophil cytoplasm antibody-associated vasculitis: 2020 update
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    The Journal of rheumatology
  5. Lee, T. C., Wilson, M. G., Lawandi, A. & McDonald, E. G.
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    Proton pump inhibitors vs. histamine-2 receptor antagonists likely increase mortality in critical care: an updated meta-analysis
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    The American journal of medicine
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